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        Nc2Eye

           A curated ncRNAomics knowledgebase for bridging basic and clinical research in eye diseases.

Detail of diabetic retinopathy (DR)
ncRNA name rno-miR-450a
ncRNA Category miRNA
Disease name diabetic retinopathy (DR)
Species Rattus norvegicus
Tissues/Cell_line retinal endothelial cells (RECs)
Methods miRNA RT-PCR Array, qRT-PCR
Expression pattern up-regulated
Functional description In RECs, 11 of the 15 most upregulated miRNAs were verified to be significantly increased in the RECs of diabetic rats by qRT-PCR. Five of the most downregulated miRNAs were confirmed to be significantly decreased in the RECs of diabetic rats.
PubMed ID 21498619
Year 2011
Title MicroRNAs in early diabetic retinopathy in streptozotocin-induced diabetic rats.
Drug-related ncRNA NO

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